[Regulation of glucose and fatty acid metabolism in skeletal muscle during contraction]. / Regulação do metabolismo de glicose e ácido graxo no músculo esquelético durante exercício físico.
Arq Bras Endocrinol Metabol
; 55(5): 303-13, 2011 Jun.
Article
em Pt
| MEDLINE
| ID: mdl-21881812
The glucose-fatty acid cycle explains the preference for fatty acid during moderate and long duration physical exercise. In contrast, there is a high glucose availability and oxidation rate in response to intense physical exercise. The reactive oxygen species (ROS) production during physical exercise suggests that the redox balance is important to regulate of lipids/carbohydrate metabolism. ROS reduces the activity of the Krebs cycle, and increases the activity of mitochondrial uncoupling proteins. The opposite effects happen during moderate physical activity. Thus, some issues is highlighted in the present review: Why does skeletal muscle prefer lipids in the basal and during moderate physical activity? Why does glucose-fatty acid fail to carry out their effects during intense physical exercise? How skeletal muscles regulate the lipids and carbohydrate metabolism during the contraction-relaxation cycle?
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Exercício Físico
/
Músculo Esquelético
/
Ácidos Graxos
/
Glucose
Limite:
Animals
/
Humans
Idioma:
Pt
Revista:
Arq Bras Endocrinol Metabol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil