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Diagnostic performance of combined cardiac MRI for detection of coronary artery disease.
de Mello, Ricardo Andrade Fernades; Nacif, Marcelo Souto; dos Santos, Alair Augusto Sarmet M D; Cury, Ricardo Caldeira; Rochitte, Carlos Eduardo; Marchiori, Edson.
Afiliação
  • de Mello RA; Hospital de Clinicas de Niterói - HCN, Niterói, RJ, Brazil. ricardoafmello@gmail.com
Eur J Radiol ; 81(8): 1782-9, 2012 Aug.
Article em En | MEDLINE | ID: mdl-21664778
OBJECTIVE: To evaluate the diagnostic performance of stress perfusion cardiac MR (CMR) for detecting significant CAD (≥70% narrowing) in comparison with invasive coronary angiography (ICA) as a reference standard. METHODS: Examinations of 54 patients who underwent both stress perfusion CMR and ICA for investigation of CAD between 2007 and 2009 were evaluated. The CMR protocol included dipyridamole stress and rest perfusion, stress and rest cine MRI for assessment of ventricular function and delayed gadolinium enhancement for assessment of myocardial viability and detection of infarction. CMR interpretation was performed by 2 observers blinded to the results of ICA and the clinical history. RESULTS: From a total of 54 patients, 37 (68.5%) showed significant CAD in 71 coronary territories. A perfusion defect was detected in 35 patients and in 69 coronary territories. Individual stress perfusion CMR evaluation showed the highest accuracy (83%) of the CMR techniques. The combined analysis using all sequences increased the overall accuracy of CMR to 87%. CONCLUSION: Combination of perfusion and cine-MR during stress/rest, associated to delayed enhancement in the same protocol improves CMRI diagnostic accuracy and sensitivity for patients with significant coronary stenosis, and may therefore be helpful for risk stratification and defining treatment strategies.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnica de Subtração / Angiografia por Ressonância Magnética / Imagem Cinética por Ressonância Magnética / Imagem de Perfusão do Miocárdio Tipo de estudo: Diagnostic_studies / Guideline Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Radiol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnica de Subtração / Angiografia por Ressonância Magnética / Imagem Cinética por Ressonância Magnética / Imagem de Perfusão do Miocárdio Tipo de estudo: Diagnostic_studies / Guideline Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Radiol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irlanda