Recent patents on the synthesis and application of silica nanoparticles for drug delivery.
Recent Pat Biotechnol
; 5(1): 54-61, 2011 Apr.
Article
em En
| MEDLINE
| ID: mdl-21517744
Drug delivery systems are designed to improve therapy efficacy as well as patient compliance. This could be accomplished by specifically targeting a medication intact to its active site, therefore reducing side-effects and enabling high local drug concentrations. Silica nanoparticles have gained ground in the biomedical field for their biocompatibility and biodegradability, being themselves inert and stable, thus enabling a variety of formulation designs for application in the pharmaceutical industry. This paper is a review of the recent patents on the applications of silica nanoparticles for drug delivery and their preparation. The review will focus on the different techniques available to obtain silica nanoparticles with variable morphology and their drug targeting applications, providing an overview of silica particles synthesis described in the literature.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Patentes como Assunto
/
Portadores de Fármacos
/
Dióxido de Silício
/
Nanopartículas
Limite:
Humans
Idioma:
En
Revista:
Recent Pat Biotechnol
Assunto da revista:
BIOTECNOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Emirados Árabes Unidos