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Relationship of glomerular filtration rate and serum CK activity after resistance exercise in women.
Machado, Marco; Zini, Elida N; Valadão, Samara D; Amorim, Mayra Z; Barroso, Tiago Z; de Oliveira, Wilkes.
Afiliação
  • Machado M; Department of Physical Education, Universitary Foundation of Itaperuna, Itaperuna, Brazil. marcomachado1@gmail.com
Int Urol Nephrol ; 44(2): 515-21, 2012 Apr.
Article em En | MEDLINE | ID: mdl-21505752
The aim of study was to assess the correlation between the changes in serum CK activity after a resistance exercise and renal function measured by glomerular filtration rate (eGFR). Twenty-nine trained women (32 ± 10 years; 157 ± 4 cm; 58.8 ± 6.4 kg) performed a resistance exercise session with 17 exercises with 3 × 12 repetitions in a circuit training fashion. Subjects provided blood samples prior to exercise session (PRE), and at 24, 48, and 72 h following exercise session for creatine kinase (CK) and creatinine. 24-Urine samples were collected before and 72 h after exercises. eGFR was obtained by the three most recommended methods (MDRD; MCQE; Cockcroft-Gault). After the exercise session, serum CK activity increase up 1.68 times (P < 0.01). Serum creatinine increased 25.5% (P = 0.0000) while urinary creatinine decreased on average 6.4% (P = 0.0422). eGFR decreased in all formulas: MDRD by 21.5%, MCQE by 14.2%, and C-G by 17% (all with P < 0.01). Ccr also decreased (-22.9%, P < 0.01). The index of correlation was significant for MDRD (r = -0.924; P < 0.01), C-G (r = -0.884; P < 0.01), and MQCE (r = -0.644; P < 0.05). In conclusion, we observed a significant negative correlation between CK activity and the eGFR indices of renal function.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância ao Exercício / Creatinina / Taxa de Filtração Glomerular / Rim Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Female / Humans Idioma: En Revista: Int Urol Nephrol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tolerância ao Exercício / Creatinina / Taxa de Filtração Glomerular / Rim Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Female / Humans Idioma: En Revista: Int Urol Nephrol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda