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Early expression in mice of genetic resistance to intestinal amebiasis.
Anaya-Velázquez, F; Underdown, B J.
Afiliação
  • Anaya-Velázquez F; Intituto de Inv. en Biología Experimental, Facultad de Química, Universidad de Guanajuato, México.
Arch Invest Med (Mex) ; 21 Suppl 1: 53-6, 1990.
Article em En | MEDLINE | ID: mdl-2136503
Some strains of mice are known to be relatively resistant to hepatic or intestinal amebic infections. In order to know if the intestinal resistance is expressed few hours after infection, we inoculated axenic amebae in three inbred strains of mice either by direct intracecal injection or by infection of a washed-closed cecal loop. We found that amebae do not survive in conventional animals but they colonize longer in animals with the cecal loop. However, the survival was low after 24 hours postinfection. Balb/c mice were more susceptible and CBA mice more resistant. Our results suggest that genetic resistance to intestinal amebiasis is expressed in mice in the early phases of infection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disenteria Amebiana / Camundongos Endogâmicos BALB C / Camundongos Endogâmicos CBA / Camundongos Endogâmicos C3H Limite: Animals Idioma: En Revista: Arch Invest Med (Mex) Ano de publicação: 1990 Tipo de documento: Article País de publicação: México
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disenteria Amebiana / Camundongos Endogâmicos BALB C / Camundongos Endogâmicos CBA / Camundongos Endogâmicos C3H Limite: Animals Idioma: En Revista: Arch Invest Med (Mex) Ano de publicação: 1990 Tipo de documento: Article País de publicação: México