[Biochemical evaluation on rural workers exposed to pesticides]. / Evaluación bioquímica de trabajadores rurales expuestos a pesticidas.
Medicina (B Aires)
; 70(6): 489-98, 2010.
Article
em Es
| MEDLINE
| ID: mdl-21163734
Pesticides are used in agriculture to protect crops but may represent a potential risk to farmers and the environment. The aim of this work was to evaluate horticultural workers exposed to pesticide, categorized by: direct exposure (n = 45), indirect exposure (n = 50) and controls (n = 50) using exposure and effect biomarkers: cholinesterase (ChE), acetylcholinesterase (AChE), catalase (CAT), lipid peroxidation (TBARS), Damage Index Comet Assay (IDEC) and Damage Index Repair Assay (IDER). Our results show: a) an AChE inhibition in directly and indirectly exposed population (p < 0.001), b) significant increase in the levels of TBARS in direct exposure (p < 0.001), c) the CAT reduction was significant (p < 0.01), d) a significant increase in IDEC and IDER in both exposed groups (p < 0.001). Our results evidence variations in oxidative balance and DNA damage in exposed workers. These findings represent a contribution to the sub-clinical evaluation of subjects exposed to agrochemicals in our country.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Praguicidas
/
Dano ao DNA
/
Peroxidação de Lipídeos
/
Exposição Ocupacional
/
Doenças dos Trabalhadores Agrícolas
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Medicina (B Aires)
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Argentina