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Lepromatous leprosy associated with the use of anti-TNF α therapy: case report.
Freitas, Daniele S; Machado, Natalia; Andrigueti, Fernando V; Reis Neto, Edgard T; Pinheiro, Marcelo M.
Afiliação
  • Freitas DS; Rheumatology Department, Universidade Federal de São Paulo, Brazil.
Rev Bras Reumatol ; 50(3): 333-9, 2010.
Article em En, Pt | MEDLINE | ID: mdl-21125169
TNF blockers have been used in the treatment of several types of chronic inflammatory arthritis, especially rheumatoid arthritis. However, many doubts regarding the safety and high risk of infectious diseases in these patients remain. The main objective of this report was to present a case of lepromatous leprosy in a rheumatoid arthritis patient using TNF blockers. The development of adverse events should be rigorously observed, especially those related to infectious agents. Thus, appropriate investigation of skin lesions in patients receiving anti-TNFα therapy is recommended, as the initial clinical manifestation may be unusual, particularly in endemic regions in Brazil.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hanseníase Virchowiana / Fator de Necrose Tumoral alfa / Anticorpos Monoclonais Tipo de estudo: Risk_factors_studies Limite: Adult / Humans / Male Idioma: En / Pt Revista: Rev Bras Reumatol Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hanseníase Virchowiana / Fator de Necrose Tumoral alfa / Anticorpos Monoclonais Tipo de estudo: Risk_factors_studies Limite: Adult / Humans / Male Idioma: En / Pt Revista: Rev Bras Reumatol Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil