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[Cineventriculography with radionuclides and intravenous dipyridamole in the prognostic evaluation after acute myocardial infarction]. / Cineventriculografia com radionuclídeos e dipiridamol venoso na avaliação prognóstica após infarto agudo do miocárdio.
Pantoja, M R; Futuro, D O; Escosteguy, C C; de Almeida, L A; Esteves, R N; Pinto, J C; Saad, E A.
Afiliação
  • Pantoja MR; Hospital Universitário da Universidade Federal do Rio de Janeiro.
Arq Bras Cardiol ; 55(3): 175-9, 1990 Sep.
Article em Pt | MEDLINE | ID: mdl-2095723
PURPOSE: To evaluate safety and usefulness of dipyridamole-radionuclide ventriculography (D-RVG), soon after acute myocardial infarction (MI), in the prediction of future cardiac events. Traditionally performed tests were also compared. PATIENTS AND METHODS: Forty-one patients (4 females) with recent MI underwent rest and dipyridamole (0.58 mg/kg of body weight) radionuclide ventriculography. The criteria for a positive test for ischemia was failure to increase left ventricular ejection fraction in 0.05 from baseline value. All patients had also coronary angiography and 36 patients underwent thallium-201 scintigraphy for comparison. The mean follow-up was 16 +/- 3 months. The following findings were considered future for events: cardiac death, reinfarction, significant angina or heart failure. RESULTS: During the follow-up 18 of the 20 patients who had cardiac events had shown positive dipyridamole-RVG, as opposed to 5 of 21 event-free patients (p less than 0.01). The ventriculographic criteria for a positive test and dipyridamole left ventricular ejection fraction were the strongest predictors of those medical events (p less than 0.01 and p less than 0.001). Among the 36 patients who had thallium-201 imaging, 16 subsequently had cardiac events and the scans were positive in 82% (p less than 0.01). Twelve (29%) patients experienced reactions during dipyridamole infusion although no fatal complications were noted. CONCLUSION: Dipyridamole-RVG is relatively safe and a sensitive predictor of future cardiac events soon after acute MI, although additional experience is required before this new technique should be routinely recommended as an alternative approach.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ventriculografia com Radionuclídeos / Dipiridamol / Infarto do Miocárdio Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: Pt Revista: Arq Bras Cardiol Ano de publicação: 1990 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ventriculografia com Radionuclídeos / Dipiridamol / Infarto do Miocárdio Tipo de estudo: Observational_studies / Prognostic_studies Limite: Female / Humans / Male Idioma: Pt Revista: Arq Bras Cardiol Ano de publicação: 1990 Tipo de documento: Article País de publicação: Brasil