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Exfoliative cytology of the oral mucosa: comparison of two collection methods.
Queiroz, Juliana Brusadin; Lima, Celina Faig; Burim, Rafael Augusto; Brandao, Adriana Aigotti Haberbeck; Cabral, Luiz Antonio Guimaraes; Almeida, Janete Dias.
Afiliação
  • Queiroz JB; Oral Biopathology, Sao Jose dos Campos Dental School, Sao Paulo State University, SP, Brazil.
Gen Dent ; 58(5): e196-9, 2010.
Article em En | MEDLINE | ID: mdl-20829152
This study compared the sampling efficacy of a cytobrush and metal spatula for exfoliative cytology of the oral mucosa. Thirty students with no detectable oral alterations upon clinical examination were submitted to exfoliative cytology of the lateral border of the tongue, using a metal spatula on the left side and a cytobrush on the right side. The smears were stained using the Papanicolaou technique and evaluated for cellularity, cell type, cell distribution, homogeneity, and cellular distortion, as well as the presence of mucus, inflammatory infiltrate, and hemorrhage. A statistical test (Z-test) with a 95% confidence interval (CI) showed a significant difference between the metal spatula and cytobrush in terms of cellularity (p = 0.02) and homogeneity (p = 0.01). No difference between the two methods was observed regarding cell type (p = 0.4, Z-test) or cell distribution for the 95% confidence interval (p = 0.2, Fisher's test). Cell distortion and the presence of mucus were observed in five cases that used the metal spatula and in two cases that used the cytobrush. No hemorrhage or inflammatory infiltrate was detected in any of the slides. Based on the results of this study, the cytobrush produced qualitatively better smears in terms of cellularity and homogeneity compared to the metal spatula.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Língua / Citodiagnóstico / Mucosa Bucal Limite: Humans Idioma: En Revista: Gen Dent Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Língua / Citodiagnóstico / Mucosa Bucal Limite: Humans Idioma: En Revista: Gen Dent Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos