Povidone-iodine against sodium hypochlorite as skin antiseptics in volunteers.
Am J Infect Control
; 38(10): 822-5, 2010 Dec.
Article
em En
| MEDLINE
| ID: mdl-20817318
BACKGROUND: This study was conducted to compare the antiseptic efficacy of sodium hypochlorite of electrochemical production with that of povidone-iodine in human voluntaries. METHODS: Three areas of 25 cm(2) each were selected from the forearms; 1 was designated as control to determine the baseline bacterial count; and 2 more were selected to swab 10% povidone-iodine or 10% sodium hypochlorite. Every volunteer was studied on 3 separated occasions. Quantitative skin cultures were performed on agar plates containing a neutralizer. RESULTS: Forty-eight healthy subjects were enrolled for a total of 144 determinations for every antiseptic and control. The bacterial counts from the control areas showed a median of 1500 colony-forming units (CFU)/cm(2). For the areas treated with sodium hypochlorite, the median was 192 CFU/cm(2). For the areas treated with povidone-iodine, the median was 231 CFU/cm(2). When the colony counts for the areas treated with antiseptics were compared with those of the controls, the difference was significant (Kruskal-Wallis test (H) = 55.7, P < .001). The difference in counts between the areas treated with antiseptics was not significant (difference in z values <1960). CONCLUSION: The present study did not find differences in antiseptic action between 10% povidone iodine and 10% sodium hypochlorite.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Povidona-Iodo
/
Pele
/
Hipoclorito de Sódio
/
Anti-Infecciosos Locais
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Infect Control
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Estados Unidos