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Povidone-iodine against sodium hypochlorite as skin antiseptics in volunteers.
Alvarez, Jose A; Macias, Juan H; Macias, Alejandro E; Rodríguez, Edmundo; Muñoz, Juan M; Mosqueda, Juan L; Ponce de Leon, Samuel.
Afiliação
  • Alvarez JA; University of Guanajuato, 20 de Enero 929, Leon Guanajuato, Mexico. micros_iesus@yahoo.com
Am J Infect Control ; 38(10): 822-5, 2010 Dec.
Article em En | MEDLINE | ID: mdl-20817318
BACKGROUND: This study was conducted to compare the antiseptic efficacy of sodium hypochlorite of electrochemical production with that of povidone-iodine in human voluntaries. METHODS: Three areas of 25 cm(2) each were selected from the forearms; 1 was designated as control to determine the baseline bacterial count; and 2 more were selected to swab 10% povidone-iodine or 10% sodium hypochlorite. Every volunteer was studied on 3 separated occasions. Quantitative skin cultures were performed on agar plates containing a neutralizer. RESULTS: Forty-eight healthy subjects were enrolled for a total of 144 determinations for every antiseptic and control. The bacterial counts from the control areas showed a median of 1500 colony-forming units (CFU)/cm(2). For the areas treated with sodium hypochlorite, the median was 192 CFU/cm(2). For the areas treated with povidone-iodine, the median was 231 CFU/cm(2). When the colony counts for the areas treated with antiseptics were compared with those of the controls, the difference was significant (Kruskal-Wallis test (H) = 55.7, P < .001). The difference in counts between the areas treated with antiseptics was not significant (difference in z values <1960). CONCLUSION: The present study did not find differences in antiseptic action between 10% povidone iodine and 10% sodium hypochlorite.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Povidona-Iodo / Pele / Hipoclorito de Sódio / Anti-Infecciosos Locais Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Infect Control Ano de publicação: 2010 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Povidona-Iodo / Pele / Hipoclorito de Sódio / Anti-Infecciosos Locais Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Infect Control Ano de publicação: 2010 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos