Neurotoxocariasis associated with lower motor neuron disease. Report of one case.
Rev Med Chil
; 138(4): 483-6, 2010 Apr.
Article
em En
| MEDLINE
| ID: mdl-20668798
We report a 51-year-old male with a history of palpitations, hepatopathy and hypercholesterolemia, who habitually ate raw goat meat, and developed general fasciculations, muscle cramps in the lower limbs, distal muscle weakness and wasting, without upper motor neuron signs or sensory abnormalities. Diagnostic workup revealed positive antibodies against Toxocara canis in the serum and cerebrospinal fluid. Nerve conduction studies revealed a proximal and distal axonal lesion of motor nerves and needle electromyography was indicative of acute and chronic denervation with giant motor unit action potentials. Despite a therapy with albendazole and riluzole, muscle weakness and wasting further progressed and affected also the respiratory muscles. Followup nerve conduction studies and electromyography confirmed progression of the axonal degeneration. Whether lower motor neuron disease was causally related to neurotoxocariasis or due to a general metabolic defect, remains speculative.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença dos Neurônios Motores
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Toxocara canis
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Toxascaríase
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Helmintíase do Sistema Nervoso Central
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Rev Med Chil
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Áustria
País de publicação:
Chile