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[Presence of B cell clones in acute myelomonocytic leukemia]. / Hallazgo de células clonales B en leucemia mielomonocítica aguda.
Novoa, Viviana; Nuñez, Neri; Cervellini, Mirta; Starosta, Aida; Carballo, Orlando G.
Afiliação
  • Novoa V; Laboratorio de Inmunología, Unidad de Inmunología, Hospital de Agudos Dr. Carlos G. Durand, Buenos Aires, Argentina. novoaviviana@yahoo.com.ar
Medicina (B Aires) ; 70(2): 163-5, 2010.
Article em Es | MEDLINE | ID: mdl-20447900
The coexistence of acute myeloid leukemia and chronic lymphocytic leukemia in the same patient is rare. The majority of the cases correspond to patients that developed acute leukemia during the evolutionary course of a chronic lymphatic leukemia following treatment with chemotherapy drugs. We report a case of acute myelomonocytic leukemia concurrent with untreated B-cell chronic lymphocytic leukemia in which the use of flow cytometry analysis with a large panel of monoclonal antibodies, allowed the demonstration of different pathological populations and determine immunophenotyping patterns. Published cases of simultaneous chronic lymphocytic leukemia and acute leukemia are reviewed. The use of multiparametric flow cytometry to differentiate the populations demonstrates the utility of this technology in the diagnosis of these hematological malignancies.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Leucemia Linfocítica Crônica de Células B / Leucemia Mielomonocítica Aguda / Anticorpos Monoclonais / Neoplasias Primárias Múltiplas Limite: Aged / Humans / Male Idioma: Es Revista: Medicina (B Aires) Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Argentina País de publicação: Argentina
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Leucemia Linfocítica Crônica de Células B / Leucemia Mielomonocítica Aguda / Anticorpos Monoclonais / Neoplasias Primárias Múltiplas Limite: Aged / Humans / Male Idioma: Es Revista: Medicina (B Aires) Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Argentina País de publicação: Argentina