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Effects of physical training on the immune system in diabetic rats.
Crespilho, Daniel Maciel; de Almeida Leme, José Alexandre Curiacos; de Mello, Maria Alice Rostom; Luciano, Eliete.
Afiliação
  • Crespilho DM; Department of Physical Education, São Paulo State University (UNESP), Rio Claro-SP, Brazil.
Int J Diabetes Dev Ctries ; 30(1): 33-7, 2010 Jan.
Article em En | MEDLINE | ID: mdl-20431804
AIMS: This study aims to investigate the influence of physical training on the immune system of diabetic rats. MATERIALS AND METHODS: Adult male Wistar rats were distributed into Sedentary Control (SC), Trained Control (TC), Sedentary Diabetic (SD) and Trained Diabetic (TD) groups were used. Diabetes was induced by alloxan (32 mg/bw-i.v.). Training protocol consisted of swimming, at 32 +/- 1 degrees C, one hour/day, five days/week, supporting an overload equivalent to 5% of the body weight, during four weeks. At the end of the experiment the rats were sacrificed by decapitation and blood samples were collected for glucose, insulin, albumin, hematocrit determinations, total and differential leukocyte counting. Additionally, liver samples for glycogen analyses were obtained. RESULTS: The results were analyzed by one way at a significance level of 5%. Diabetes reduced blood insulin, liver glycogen stores and increased blood glucose and neutrophil count. Physical training restored glycemia, liver glycogen levels, neutrophils and lymphocytes count in diabetic rats. CONCLUSIONS: In summary, physical training was able to improve metabolic and immunological aspects in the experimental diabetic rats.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int J Diabetes Dev Ctries Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int J Diabetes Dev Ctries Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Índia