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Cervical cancer prevention: new tools and old barriers.
Scarinci, Isabel C; Garcia, Francisco A R; Kobetz, Erin; Partridge, Edward E; Brandt, Heather M; Bell, Maria C; Dignan, Mark; Ma, Grace X; Daye, Jane L; Castle, Philip E.
Afiliação
  • Scarinci IC; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-4410, USA. scarinci@uab.edu
Cancer ; 116(11): 2531-42, 2010 Jun 01.
Article em En | MEDLINE | ID: mdl-20310056
Cervical cancer is the second most common female tumor worldwide, and its incidence is disproportionately high (>80%) in the developing world. In the United States, in which Papanicolaou (Pap) tests have reduced the annual incidence to approximately 11,000 cervical cancers, >60% of cases are reported to occur in medically underserved populations as part of a complex of diseases linked to poverty, race/ethnicity, and/or health disparities. Because carcinogenic human papillomavirus (HPV) infections cause virtually all cervical cancer, 2 new approaches for cervical cancer prevention have emerged: 1) HPV vaccination to prevent infections in younger women (aged < or =18 years) and 2) carcinogenic HPV detection in older women (aged > or =30 years). Together, HPV vaccination and testing, if used in an age-appropriate manner, have the potential to transform cervical cancer prevention, particularly among underserved populations. Nevertheless, significant barriers of access, acceptability, and adoption to any cervical cancer prevention strategy remain. Without understanding and addressing these obstacles, these promising new tools for cervical cancer prevention may be futile. In the current study, the delivery of cervical cancer prevention strategies to these US populations that experience a high cervical cancer burden (African-American women in South Carolina, Alabama, and Mississippi; Haitian immigrant women in Miami; Hispanic women in the US-Mexico Border; Sioux/Native American women in the Northern Plains; white women in the Appalachia; and Vietnamese-American women in Pennsylvania and New Jersey) is reviewed. The goal was to inform future research and outreach efforts to reduce the burden of cervical cancer in underserved populations.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Female / Humans País/Região como assunto: America do norte / Asia / Caribe / Haiti Idioma: En Revista: Cancer Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Female / Humans País/Região como assunto: America do norte / Asia / Caribe / Haiti Idioma: En Revista: Cancer Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos