Relative acidities and structure analysis of cis and trans isomers of 1,5-oxazaspiro[5.5] undecane derivatives by multinuclear magnetic resonance.

Guerrero-Alvarez, Jorge Antonio; Mas-Ku, Wendy Paloma; Garcías-Morales, Cesar; Ariza-Castolo, Armando

Guerrero-Alvarez, Jorge Antonio; Mas-Ku, Wendy Paloma; Garcías-Morales, Cesar; Ariza-Castolo, Armando.

Afiliação

Guerrero-Alvarez JA; Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Col. Chamilpa, Cuernavaca Morelos 62210, Mexico. jguerrero@ciq.uaem.mx

Magn Reson Chem ; 48(5): 356-61, 2010 May.

Article em En | MEDLINE | ID: mdl-20306516

RESUMO

The relative acidities of the cis and trans isomers of a series of 1,5-oxazaspiro[5.5]undecane derivatives were determined by measuring DeltapK in acid-base titrations followed by (1)H NMR. Relative structural stabilities were determined by measuring substituent chemical shift and gamma-gauche effects in (13)C, (15)N, and (17)O NMR. Crystallographic characterization of a model spiro[5.5]undecane is presented to support the basicity in solid state.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Magn Reson Chem Assunto da revista: QUIMICA Ano de publicação: 2010 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido

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