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Cutaneous mycoflora and CD4:CD8 ratio of cats infected with feline immunodeficiency virus.
Reche, Archivaldo; Daniel, Alexandre G T; Lazaro Strauss, Telma C P; Taborda, Carlos P; Vieira Marques, Shirlei A; Haipek, Kátia; Oliveira, Lilian J; Monteiro, Janaína M; Kfoury, José R.
Afiliação
  • Reche A; Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, CEP: 05508-270 São Paulo, Brazil. valdorec@usp.br
J Feline Med Surg ; 12(4): 355-8, 2010 Apr.
Article em En | MEDLINE | ID: mdl-20156698
This study was designed to compare cutaneous mycoflora isolation and CD4+:CD8+ ratio in feline immunodeficiency virus (FIV)-infected cats with that in FIV-uninfected cats. Sixty cats were examined. Twenty-five were FIV-infected cats and 35 were FIV-uninfected cats. All 60 cats were FeLV-negative. Fungi were speciated and immunophenotyping of peripheral CD4+ and CD8+ T lymphocytes was performed. At least one fungal colony was isolated from 22/25 (88%) FIV-infected cats. Among the FIV-uninfected cats fungal colonies were recovered from 13/35 (37%) specimens. Dermatophytes were recovered from 2/25 (8%) FIV-infected cats (one Microsporum gypseum, one Microsporum canis) and 3/35 (8.5%) FIV-uninfected cats (M gypseum). Malassezia species was the most commonly isolated organism from both groups of cats (51.6%). Malassezia species was more commonly isolated from FIV-infected cats than FIV-uninfected cats (84% vs 28.6%). The CD4+ to CD8+ lymphocyte ratio for FIV-infected cats was significantly lower than the CD4+ to CD8+ ratio in the FIV-uninfected cats. The CD4+ to CD8+ lymphocyte ratio for FIV-infected cats with cutaneous overall fungal isolation was significantly lower than the CD4:CD8 lymphocyte ratio in the FIV-infected cats but without cutaneous fungal isolation. We can conclude that immunologic depletion due to retroviral infection might represent a risk factor to cutaneous fungal colonization in cats.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças do Gato / Síndrome de Imunodeficiência Adquirida Felina / Relação CD4-CD8 / Vírus da Imunodeficiência Felina / Dermatomicoses Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: J Feline Med Surg Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças do Gato / Síndrome de Imunodeficiência Adquirida Felina / Relação CD4-CD8 / Vírus da Imunodeficiência Felina / Dermatomicoses Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: J Feline Med Surg Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2010 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido