[Experimental model in rats for the development of pseudoarthrosis]. / Modelo experimental em ratos para o desenvolvimento de pseudoartrose.
Rev Col Bras Cir
; 36(6): 514-8, 2009 Dec.
Article
em Pt
| MEDLINE
| ID: mdl-20140396
OBJECTIVE: We sought to describe a new model of pseudoarthrosis in rats free of pathogenic species (Rattus norvegicus albinus - SPF). METHODS: The animals were randomly distributed into two groups were used: Group 1 - Control (n =6); Group 2 - Experimental (n =6). In the Control group an access to the femur followed by the synthesis of the muscular and skin layers was done. The Experimental group was submitted to osteotomy of the femur and a pedicle flap of the fascia lata was interposed between the segments resulting from the surgically induced fracture. The procedure was carried on with both alignment and approximation of the fractured bone through the use of mononylon thread introduced into holes created in the proximal and distal. RESULTS: Radiological and anatomopathological studies showed the absence of bone consolidation with persistence of fibro-osteoid tissue up to 120 days of follow-up. CONCLUSION: The experimental model is suitable for the development of a pseudoarthrosis in rats.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteotomia
/
Pseudoartrose
/
Modelos Animais de Doenças
/
Fraturas não Consolidadas
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
Pt
Revista:
Rev Col Bras Cir
Ano de publicação:
2009
Tipo de documento:
Article
País de publicação:
Brasil