Synergistic effects of the Lactobacillus acidophilus surface layer and nisin on bacterial growth.
Appl Environ Microbiol
; 76(3): 974-7, 2010 Feb.
Article
em En
| MEDLINE
| ID: mdl-19948852
We have previously described a murein hydrolase activity for the surface layer (S-layer) of Lactobacillus acidophilus ATCC 4356. Here we show that, in combination with nisin, this S-layer acts synergistically to inhibit the growth of pathogenic Gram-negative Salmonella enterica and potential pathogenic Gram-positive bacteria, Staphylococcus aureus and Bacillus cereus. In addition, bacteriolytic effects were observed for the Gram-positive species tested. We postulate that the S-layer enhances the access of nisin into the cell membrane by enabling it to cross the cell wall, while nisin provides the sudden ion-nonspecific dissipation of the proton motive force required to enhance the S-layer murein hydrolase activity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Conservantes de Alimentos
/
Lactobacillus acidophilus
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Antibacterianos
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N-Acetil-Muramil-L-Alanina Amidase
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Nisina
Idioma:
En
Revista:
Appl Environ Microbiol
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Estados Unidos