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[Hepatitis C in Venezuela. Preliminary report]. / Hepatitis C en Venezuela. Comunicación preliminar.
Muller, G; Zabaleta, M; Caldera, L H; Bianco, N; Machado, I V.
Afiliação
  • Muller G; Centro Nacional de Referencia en Inmunología Clínica, SAS-UCV.
G E N ; 44(4): 336-42, 1990.
Article em Es | MEDLINE | ID: mdl-1967086
Five hundred serum samples from volunteers blood donors were investigated in order to determine the presence of anti-HCV antibodies by an enzyme-linked immunoassay recently developed worldwide. Prevalence of true-positive samples was 1.2% (6/500), 2 fold higher than the reported prevalence in most of the industrialized countries. From these 6 sera, one (16.6%) showed simultaneous reactivity for HBV anticore antibody. Three sera (25%) from 12 patients with diagnosis of Non-A Non-B hepatitis were reactive for anti-HCV antibodies while in a group of 32 sera with negative HAV and HBV screening, 4 (12.5%) showed anti-HCV antibodies. Two samples out of 16 sera persistently positive for anticore demonstrated the presence of anti-HCV antibodies. The anti-HCV antibodies were undetectable in two cases of autoimmune chronic hepatitis. Our results indicate that in Venezuela, HCV represents a significant problem of public health coexisting in certain cases with HBV infection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Venezuela Idioma: Es Revista: G E N Ano de publicação: 1990 Tipo de documento: Article País de publicação: Venezuela
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Venezuela Idioma: Es Revista: G E N Ano de publicação: 1990 Tipo de documento: Article País de publicação: Venezuela