The pathophysiology of the acute phase of human bartonellosis resembles AIDS.
Med Hypotheses
; 74(1): 45-9, 2010 Jan.
Article
em En
| MEDLINE
| ID: mdl-19665314
Human bartonellosis is a South American anthroponosis caused by Bartonella bacilliformis. The disease has an acute phase characterized by invasion of red blood cells by parasites, and consequent severe anemia; and a chronic phase presenting with benign vascular tumors. During the acute phase, affected individuals are prone to developing opportunistic infections with a variety of organisms similar to the ones seen in AIDS. After antibiotic treatment is instituted, a subgroup of patients may develop atypical symptoms which potentially represent clinical manifestations of the restoration of macrophage function. We speculate that the pathophysiology of the acute phase of human bartonellosis resembles AIDS, with a period of immunosuppression following the infection and later, clinical manifestations of immune reconstitution subsequent to treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Bartonella
/
Síndrome da Imunodeficiência Adquirida
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
/
Humans
País/Região como assunto:
America do sul
Idioma:
En
Revista:
Med Hypotheses
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Peru
País de publicação:
Estados Unidos