[Lymphoproliferative disorders after renal transplantation in a child]. / Trastorno linfoproliferativo post trasplante renal en un niño.
Rev Med Chil
; 137(3): 405-10, 2009 Mar.
Article
em Es
| MEDLINE
| ID: mdl-19621184
Post transplant lymphoproliferative disorder (PTLD) is the commonest form of post transplant malignancy in children. The incidence in renal transplant recipients varies between 2%-4%. They are characterized by uncontrolled B lymphocyte proliferation, in most cases driven by Epstein Barr virus (EBV). They are more common in younger children, EBV seronegative patients and those who receive aggressive immunosuppression. PTLD commonly presents in an unspecific form and it requires high suspicion rate for its diagnosis, especially in children with risk factors. We report a twelve year-old girl who developed fever, sore throat and lymph node enlargement, six months after receiving a renal allograft. Laboratory assessment and imaging studies were compatible with PTLD, which was confirmed by biopsy. Treatment was reduction of immunosuppression and surveillance. The patient had a favorable evolution.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Sirolimo
/
Imunossupressores
/
Transtornos Linfoproliferativos
Tipo de estudo:
Risk_factors_studies
Limite:
Child
/
Female
/
Humans
Idioma:
Es
Revista:
Rev Med Chil
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile