[Fluconazole susceptibility of invasive Candida sp isolates as determined by three methods: Bogotá - Colombia]. / Evaluación mediante tres técnicas de susceptibilidad a fluconazol en especies de Candida aisladas en pacientes con infecciones invasoras: Bogotá - Colombia.
Rev Chilena Infectol
; 26(2): 135-43, 2009 Apr.
Article
em Es
| MEDLINE
| ID: mdl-19621144
UNLABELLED: The frequency of invasive mycosis caused by Candida sp has increased significantly in immuno-compromised patients and in those under medical/surgical treatment; along with it, the use of azoles has fostered resistance. OBJECTIVE: To compare in vitro susceptibility techniques, susceptibility to fluconazol was determined by the M27-A2 method of CLSI (Clinical Laboratory Standard Institute), the disk diffusion technique in 90 invasive Candida sp isolated species (49 C albicans, 30 C. tropicalis, 5 C parapsilosis, 4 C . guilliermondii and 2 C. lusitaniae) and the E-test in 16 isolated. RESULTS: Over 90% of strains were susceptible to fluconazol. A straight correlation between disk-diffusion technique and the E-test was observed regarding the reference method (0.944 and 0.938, respectively). CONCLUSION: In our institution the use of fluconazol for invasive candidiasis is recommended, as well as the routine use of the disk-diffusion or E-test techniques in high complex hospitals in Colombia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candida
/
Testes de Sensibilidade Microbiana
/
Fluconazol
/
Antifúngicos
Limite:
Humans
País/Região como assunto:
America do sul
/
Colombia
Idioma:
Es
Revista:
Rev Chilena Infectol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Colômbia
País de publicação:
Chile