Clinical observations of cattle and buffalos with experimentally induced chronic copper poisoning.
Res Vet Sci
; 87(3): 473-8, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19487001
The susceptibility of cattle and buffalos to chronic copper poisoning (CCP) was compared by using cattle (n=10) and buffalo (n=10) steers distributed into two copper supplemented (n=6) and two control (n=4) groups. Supplemented animals received 2 mg copper (Cu)/kg body weight daily for one week, with an additional 2 mg weekly until the end of the experiment (day 105). Three liver biopsies (day 0, 45, and 105) were obtained for mineral analyses; clinical examinations and blood samples were obtained every 15days. Three supplemented cattle and two buffalos with typical manifestations of CCP died. There were no differences in the frequency of mortality between cattle and buffalos; hepatic copper concentration was higher in cattle than buffalos. These findings suggest that buffalos and cattle might be equally susceptible to CCP. However, buffalos accumulate less liver copper than cattle and have a lower threshold of hepatic Cu accumulation, which leads to clinical manifestation of CCP.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Búfalos
/
Doenças dos Bovinos
/
Cobre
Limite:
Animals
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Reino Unido