Asymmetric allylboration reactions with Soderquist's chiral 10-substituted-9-borabicyclo[3.3.2]decanes: a theoretical study.
J Org Chem
; 74(9): 3562-5, 2009 May 01.
Article
em En
| MEDLINE
| ID: mdl-19348492
Chiral B-allyl-10-substituted-9-borabicyclo[3.3.2]decanes are highly efficient reagents for the enantioselective allylboration of adehydes and ketones. In this study, we use DFT calculations to rationalize the experimentally observed reactivity and selectivity. Calculations correctly reproduced the experimental reactivity trends and enantioselectivities. Our results suggest that the origin of the facial selectivity relies strongly on steric effects.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Boro
/
Alcanos
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Estados Unidos