Undernutrition and oxidative stress as risk factors for high blood pressure in older Mexican adults.
Ann Nutr Metab
; 54(2): 119-23, 2009.
Article
em En
| MEDLINE
| ID: mdl-19295195
OBJECTIVE: To determine the relationship between undernutrition and oxidative stress as risk factors for high blood pressure (HBP) in older Mexican adults. We carried out a case-control study in a convenience sample of 62 older adults, 60-80 years of age; 32 without HBP (mean age 75.8 +/- 5.1 years) and 30 with HBP (mean age 65.2 +/- 6.8 years). METHODS: We measured serum lipoperoxide (LPO) levels, antioxidant enzymes, total antioxidant activity and lipid profile; in addition, we evaluated the nutritional status with anthropometric measurements, the Mini Nutritional Assessment and food intake frequency. Data were analyzed with Student t and odds ratio (OR) statistical tests. RESULTS: We observed significantly higher LPO levels in subjects with HBP than in normotensive subjects (0.303 +/- 0.10 vs. 0.256 +/- 0.06 micromol/l; p < 0.05). With respect to risk factors for HBP, we found an OR of 12.2 (95% CI 1.9-76.4, p < 0.01) in subjects with high LPO levels (> or = 0.320 micromol/l) and an OR of 5.0 (95% CI 1.1-23.0, p < 0.05) in those with undernutrition. CONCLUSION: Our findings suggest that high LPO levels and undernutrition are significant risk factors for HBP.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Estado Nutricional
/
Estresse Oxidativo
/
Desnutrição
/
Hipertensão
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Ann Nutr Metab
Ano de publicação:
2009
Tipo de documento:
Article
País de publicação:
Suíça