Analytical quantification of low-density lipoprotein using europium tetracycline indicator.
Luminescence
; 24(3): 189-93, 2009.
Article
em En
| MEDLINE
| ID: mdl-19291808
Low-density lipoprotein (LDL) is known as 'bad' cholesterol. If too much LDL circulates in the blood it can be retained in the walls of the arteries, causing atherosclerosis. In this paper we showed an alternative method to quantify LDL using the europium tetracycline (EuTc) indicator. The optical properties of the EuTc complex were investigated in aqueous solutions containing LDL. An enhancement was observed of the europium luminescence in the solutions with LDL compared those without the lipoprotein. A method to quantify the amount of LDL in a sample, based on EuTc enhanced luminescence, is proposed. The enhancement mechanism is also discussed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Tetraciclinas
/
Indicadores e Reagentes
/
Lipoproteínas LDL
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Luminescence
Assunto da revista:
BIOFISICA
/
BIOQUIMICA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Reino Unido