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Brain GABA and benzodiazepine receptors in hepatic encephalopathy.
Butterworth, R F.
Afiliação
  • Butterworth RF; Laboratory of Neurochemistry, André-Viallet Clinical Research Centre, Hôpital St-Luc (University of Montreal), Montreal, Quebec, Canada H2X 3J4.
Rev Invest Clin ; 42 Suppl: 137-40, 1990 Jul.
Article em En | MEDLINE | ID: mdl-19256153
Mammalian brain contains two types of benzodiazepine receptors namely the "central-type" receptor which forme part of the GABA-benzodiazepine receptor complex, and the so-called "peripheral-type" receptor found predominantly on mitocondrial membranes of astrocytes. Brain GABA-related benzodiazepine receptors are unchanged in hepatic encephalopathy. On the other hand, human and experimental hepatic encephalopathy are associated with increased densities of "peripheral type" benzodiazepine receptor. Results of several studies using agonists and antagonists of both types of benzodiazepine receptors are discussed in this review.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Encefalopatia Hepática / Astrócitos / Receptores de GABA / Receptores de GABA-A Limite: Animals / Humans Idioma: En Revista: Rev Invest Clin Assunto da revista: MEDICINA Ano de publicação: 1990 Tipo de documento: Article País de publicação: México
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Encefalopatia Hepática / Astrócitos / Receptores de GABA / Receptores de GABA-A Limite: Animals / Humans Idioma: En Revista: Rev Invest Clin Assunto da revista: MEDICINA Ano de publicação: 1990 Tipo de documento: Article País de publicação: México