Brain GABA and benzodiazepine receptors in hepatic encephalopathy.
Rev Invest Clin
; 42 Suppl: 137-40, 1990 Jul.
Article
em En
| MEDLINE
| ID: mdl-19256153
Mammalian brain contains two types of benzodiazepine receptors namely the "central-type" receptor which forme part of the GABA-benzodiazepine receptor complex, and the so-called "peripheral-type" receptor found predominantly on mitocondrial membranes of astrocytes. Brain GABA-related benzodiazepine receptors are unchanged in hepatic encephalopathy. On the other hand, human and experimental hepatic encephalopathy are associated with increased densities of "peripheral type" benzodiazepine receptor. Results of several studies using agonists and antagonists of both types of benzodiazepine receptors are discussed in this review.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Transporte
/
Encefalopatia Hepática
/
Astrócitos
/
Receptores de GABA
/
Receptores de GABA-A
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Rev Invest Clin
Assunto da revista:
MEDICINA
Ano de publicação:
1990
Tipo de documento:
Article
País de publicação:
México