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[Multivariate model to predict Streptococcus pyogenes tonsillitis]. / Modelo multivariado para predecir amigdaltis estreptócócica.
Villaseñor-Sierra, Alberto; Caballero-Hoyos, José Ramiro; Jáuregui-Lomelí, Juan José; Flores-Sánchez, Jesús; Martínez-Sandoval, Francisco.
Afiliação
  • Villaseñor-Sierra A; Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco. avillase@prodigy.net.mx
Rev Med Inst Mex Seguro Soc ; 46(4): 383-90, 2008.
Article em Es | MEDLINE | ID: mdl-19213209
OBJECTIVE: to develop a multivariate model to predict the Streptococcus pyogenes isolation in patients with acute tonsillitis. METHODS: cross-sectional analytic study on patients with acute tonsillitis without a recent history of antimicrobial consumption. We evaluated 14 signs and 18 symptoms. A pharyngeal culture was realized on 5% sheep blood agar. Group A streptococci was identified by standard methods. STATISTICAL ANALYSIS: sensitivity, specificity, predictive values, chi2, Fisher's exact test, crude and adjusted odds ratio (OR) with 95% CI using dichotomical logistic regression with direct method and Hosmer and Lemeshow-goodness-fit test. RESULTS: there were 213 participants, 37% were males; a mean age of 14.9 years. We isolated Streptococcus pyogenes in 15%, and 84 % of them had received antimicrobials. We identified signs and symptoms associated with Streptococcus pyogenes isolation: painful swallowing (OR=4.45, 95% CI = 1.13-17.53); tonsils with exudates (OR=3.20, 95% CI = 1.22-8.43); smelly breath (OR=2.78, 95% CI = 1.09-7.10); painful neck nodes (OR=2.70, 95% CI = 1.05-6.96). The presence of nasal symptoms was a protective factor (OR=0.25, 95% CI = 0.09-0.71). CONCLUSIONS: the prevalence of Streptococcus pyogenes tonsillitis was similar to other reports. We found signs and symptoms associated to Streptococcus pyogenes isolation that allowed us to elaborate a decision algorithm.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus pyogenes / Tonsilite / Modelos Teóricos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Med Inst Mex Seguro Soc Assunto da revista: MEDICINA / MEDICINA SOCIAL Ano de publicação: 2008 Tipo de documento: Article País de publicação: México
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus pyogenes / Tonsilite / Modelos Teóricos Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: Es Revista: Rev Med Inst Mex Seguro Soc Assunto da revista: MEDICINA / MEDICINA SOCIAL Ano de publicação: 2008 Tipo de documento: Article País de publicação: México