[Oncogenic osteomalacia: localization of underlying peripheral tumor with 99mTc-sestamibi scintigraphy]. / Osteomalácia oncogênica: cintilografia com sestamibi-99mTc na localização do tumor.
Arq Bras Endocrinol Metabol
; 52(9): 1505-9, 2008 Dec.
Article
em Pt
| MEDLINE
| ID: mdl-19197461
Oncogenic osteomalacia is a paraneoplastic syndrome usually induced by bone or soft tissue tumors. It is presented by the development of pain and fractures with hypophosphatemia, hyperphosphaturia, and inappropriate normal/low plasma 1,25(OH)2D3 concentration. After the removal of the tumor the complete resolution of all biochemical and clinical abnormalities is the main characteristic. A case of a 44-year-old female with difficulty in walking due to leg pain and generalized muscle weakness and hypophosphatemia, with relative hyperphosphaturia, is described. A whole-body 99mTc-sestamibi scintigraphy showed accumulation in the left thigh region, and a small tumor was detected by ultrasound examination. By removal of the tumor, a lipoma, the symptoms improved significantly after a month, with complete recovery by the fourth month. In this case, 99mTc-sestamibi scintigraphy was useful in identifying the location of the tumor, which caused oncogenic osteomalacia.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteomalacia
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Neoplasias do Sistema Nervoso Periférico
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Tecnécio Tc 99m Sestamibi
/
Compostos Radiofarmacêuticos
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Female
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Humans
Idioma:
Pt
Revista:
Arq Bras Endocrinol Metabol
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil