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[Oncogenic osteomalacia: localization of underlying peripheral tumor with 99mTc-sestamibi scintigraphy]. / Osteomalácia oncogênica: cintilografia com sestamibi-99mTc na localização do tumor.
Biagini, Gleyne Lopes Kujew; Coutinho, Priscilla Rizental; Jonasson, Thaisa Hoffman; Ueda, Cristina Emiko; Gama, Ricardo Ribeiro.
Afiliação
  • Biagini GL; Faculdade Evangélica do Paraná, Curitiba, PR, Brazil.
Arq Bras Endocrinol Metabol ; 52(9): 1505-9, 2008 Dec.
Article em Pt | MEDLINE | ID: mdl-19197461
Oncogenic osteomalacia is a paraneoplastic syndrome usually induced by bone or soft tissue tumors. It is presented by the development of pain and fractures with hypophosphatemia, hyperphosphaturia, and inappropriate normal/low plasma 1,25(OH)2D3 concentration. After the removal of the tumor the complete resolution of all biochemical and clinical abnormalities is the main characteristic. A case of a 44-year-old female with difficulty in walking due to leg pain and generalized muscle weakness and hypophosphatemia, with relative hyperphosphaturia, is described. A whole-body 99mTc-sestamibi scintigraphy showed accumulation in the left thigh region, and a small tumor was detected by ultrasound examination. By removal of the tumor, a lipoma, the symptoms improved significantly after a month, with complete recovery by the fourth month. In this case, 99mTc-sestamibi scintigraphy was useful in identifying the location of the tumor, which caused oncogenic osteomalacia.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteomalacia / Neoplasias do Sistema Nervoso Periférico / Tecnécio Tc 99m Sestamibi / Compostos Radiofarmacêuticos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: Pt Revista: Arq Bras Endocrinol Metabol Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteomalacia / Neoplasias do Sistema Nervoso Periférico / Tecnécio Tc 99m Sestamibi / Compostos Radiofarmacêuticos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: Pt Revista: Arq Bras Endocrinol Metabol Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil