[Anti-fungi activity of organic extracts from the tree Fagara monophylla (Rutaceae) in Venezuela]. / Actividad antifúngica de extractos orgánicos del árbol Fagara monophylla (Rutaceae) en Venezuela.
Rev Biol Trop
; 55(3-4): 767-75, 2007.
Article
em Es
| MEDLINE
| ID: mdl-19086382
The tree Fagara monophylla ranges throughout Tropical America. The genus Fagara has a diversity of alkaloid compounds with antibiotic properties; nevertheless, there are few reports antifungal activity of its organic compounds. Organic extracts from Venezuelan F. monophylla were tested for antimicrobial activity against Aspergillus terreus, A. flavus, Penicillium digitatum, P. funiculosum, P. citrinum, Paecilomyces and Candida albicans. Minimal Inhibitory Concentration (MIC) was determined. The susceptibility trials of organic fractions (Hex., CH2Cl2 and MeOH) showed that the highest inhibition was presented by MeOH against A. flavus (55 mm), P. digitatum (60 mm), P. funiculosum (56 mm) and C. albicans (26 mm). The activities of MeOH/EtOAc fractions 1 and 2 suggest a combined effect against A. flavus, P. digitatum and P. funiculosum. The MIC of 1 MeOH/ EtOAc subfraction activity was lower against C. albicans (32 microg/ml) and moderate (128 microg/ml) against P. digitatum. This organic extract has a great antifungal potential. The phytochemical proves and TLC testing on the organic extract, and the MeOH/EtOAc subfraction, respectively, indicated the presence of alkaloid compounds.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Rutaceae
/
Fungos Mitospóricos
/
Antifúngicos
País/Região como assunto:
America do sul
/
Venezuela
Idioma:
Es
Revista:
Rev Biol Trop
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Venezuela
País de publicação:
Costa Rica