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Performance of speech perception after cochlear implantation in DFNB1 patients.
Dalamón, Viviana; Lotersztein, Vanesa; Lipovsek, Marcela; Bèherán, Agustina; Mondino, Maria Elena; Diamante, Fernando; Pallares, Norma; Diamante, Vicente; Elgoyhen, Ana Belen.
Afiliação
  • Dalamón V; Instituto de Investigaciones en Ingenieria Genetica y Biologia Molecular, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Universidad de Buenos Aires, Buenos Aires, Argentina. dalamon@dna.uba.ar
Acta Otolaryngol ; 129(4): 395-8, 2009 Apr.
Article em En | MEDLINE | ID: mdl-19051073
CONCLUSION: There were no apparent differences in speech performance after cochlear implantation between patients with biallelic GJB2 and/or GJB6 mutations and those with deafness of unknown aetiology. These data have important implications for the selection of prognostic indicators of the outcome of cochlear implantation. OBJECTIVE: To compare performance after cochlear implantation in children with mutations in GJB2 (connexin 26) and/or GJB6 (connexin 30) and children with deafness of unknown aetiology. SUBJECTS AND METHODS: Genetic analysis and speech performance evaluation was determined in 24 patients with (n=11) and without (n=13) biallelic GJB2 and/or GJB6 mutations who underwent cochlear implantation. Speech perception skills were measured 12 and 24 months after surgery. Each patient was classified in accordance with the speech perception category (SPC). RESULTS: Overall, the two groups showed similar significant improvement in speech perception after implantation.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Percepção da Fala / Conexinas / Implante Coclear / Surdez Tipo de estudo: Observational_studies Limite: Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Acta Otolaryngol Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Percepção da Fala / Conexinas / Implante Coclear / Surdez Tipo de estudo: Observational_studies Limite: Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Acta Otolaryngol Ano de publicação: 2009 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido