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[Atherosclerosis, oxidative stress and physical activity. Review]. / Ateroesclerosis, estrés oxidativo y actividad fisica. Revisión.
Calderón, Juan Camilo; Fernández, Ana Zita; María de Jesús, Alina Isabel.
Afiliação
  • Calderón JC; Departamento de Fisiología y Bioquímica, Grupo de Fisiología del Ejercicio, Facultad de Medicina, Universidad de Antioquia, Colombia.
Invest Clin ; 49(3): 397-410, 2008 Sep.
Article em Es | MEDLINE | ID: mdl-18846779
Atherosclerosis and related diseases have emerged as the leading cause of morbidity and mortality in the western world and, therefore, as a problem of public health. Free radicals and reactive oxygen species have been suggested to be part of the pathophysiology of these diseases. It is well known that physical activity plays an important role as a public health measure by reducing the risk of developing atherosclerosis-related cardiovascular events in the general population. It is also known that physical activity increases in some tissues, the reactive oxygen species production. In this review the atherosclerosis-oxidative stress-physical activity relationship is focused on the apparent paradox by which physical activity reduces atherosclerosis and cardiovascular risk in parallel with the activation of an apparently damaging mechanism which is an increased oxidative stress. A hypothesis including the experimental and clinical evidence is presented to explain the aforementioned paradox.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Aterosclerose / Atividade Motora Limite: Humans Idioma: Es Revista: Invest Clin Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Venezuela
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Aterosclerose / Atividade Motora Limite: Humans Idioma: Es Revista: Invest Clin Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Venezuela