Prostate cryoablation: prospective analysis comparing high- and low-risk prostate cancer outcomes.
Urol Int
; 81(2): 186-90, 2008.
Article
em En
| MEDLINE
| ID: mdl-18758217
AIM: To evaluate percutaneous cryotherapy as a primary treatment option for prostate cancer, comparing different risk groups. PATIENTS AND METHODS: Forty-seven prostate cryoablation procedures were performed on 44 patients. Patients median age was 70.9, and average pretreatment PSA of 13.8 ng/dl. Patients were divided into low-risk (13 patients), high-risk (24 patients) and radiation failure patients (7 patients). The follow-up period ranged from 18 to 60 months (median 41 months). RESULTS: In the low-risk group, we found after 12 and 24 months of follow-up, 92 and 86% of patients free of PSA relapse (PSA <1 ng/ml), respectively. In the high-risk group, the PSA failure was 39 and 52.9%. For the radiation failure group, 86 and 71.4% of patients had PSA below 1 ng/dl. At 48 months of follow-up, 80% of the low-risk patients, 42.8% of the high-risk group and 71.4% of the radiation failure group were free of PSA relapse. The complication rates were low, with 13% of urinary incontinence and no cases of rectal injury. CONCLUSION: Prostate cryoablation is a viable and promising minimally invasive alternative for localized or locally advanced prostate cancer patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Criocirurgia
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Aged
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Aged80
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Urol Int
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Suíça