[Alpha-tocopherol and alpha-lipoic acid. An antioxidant synergy with potential for preventive medicine]. / El alfa-tocoferol y el acido alfa-lipoico. Una sinergia antioxidante con potencial en medicina preventiva.
Rev Invest Clin
; 60(1): 58-67, 2008.
Article
em Es
| MEDLINE
| ID: mdl-18589588
Reactive oxygen species (ROS) have been involved in the induction and progression of damage of many human disorders, such as: heart infarction, cerebral ischemia, diabetic neuropathy, Alzheimer's disease, etc. In several studies, the synergism between alpha-lipoic acid and vitamin E has been described and potent antioxidant effects can be obtained when both antioxidants are simultaneously used. This review highlights recent findings showing that the combination of alpha-lipoic acid plus vitamin E effectively reduces oxidative damage in brain and cardiac ischemia as well as in other pathological events related to ROS increasing. These antioxidants are present in a broad variety of foods, are also available in several dietary supplements and their side effects are very rare. Therefore, alpha-lipoic acid and vitamin E may play an important role in clinical preventive medicine and human nutrition.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Tióctico
/
Alfa-Tocoferol
/
Antioxidantes
Limite:
Animals
/
Humans
Idioma:
Es
Revista:
Rev Invest Clin
Assunto da revista:
MEDICINA
Ano de publicação:
2008
Tipo de documento:
Article
País de publicação:
México