Effect of chlorhexidine-thymol varnish on caries lesion development in first permanent molars.
J Clin Dent
; 19(1): 18-21, 2008.
Article
em En
| MEDLINE
| ID: mdl-18500155
OBJECTIVE: The aim of this study was to investigate the caries prevention efficacy of chlorhexidine-thymol (CHX-T) varnish on newly erupted permanent first molars. METHODS: Fifty-seven six- to eight-year-old school children were included in a program of sequential CHX-T varnish application. For inclusion, they had to have at least two homologous, newly erupted first permanent molars with visually sound occlusal surfaces. A clinical examination was used to determine the molar eruption stage, biofilm presence, and whole caries status. There were 99 pairs of molars in the study population. A split-mouth design was used where each child randomly had one first molar treated with six applications of CHX-T varnish, and the other with a placebo varnish, every 15 days for 75 days. The children were then revaluated for caries one year following the conclusion of treatment. RESULTS: Fourteen pairs of teeth presented incipient enamel caries lesions in both molars (one CHX-T and one placebo varnish), four developed lesions in the placebo-treated molars only, and eight developed lesions in CHX-T varnish-treated molar only. No significant statistical differences were found between the two groups with regard to caries increment (p = 0.20). CONCLUSION: Six applications of CHX-T varnish had no protective effect against caries development.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Timol
/
Cariostáticos
/
Clorexidina
/
Cárie Dentária
/
Anti-Infecciosos Locais
Tipo de estudo:
Clinical_trials
Limite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Clin Dent
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos