Liver and serum soluble protein changes and pathomorphology in undernourished mice with acute schistosomiasis mansoni.
Rev Soc Bras Med Trop
; 24(4): 235-43, 1991.
Article
em En
| MEDLINE
| ID: mdl-1845008
Body, liver and spleen weights; histopathology of the liver, spleen and intestines; hepatic and serum soluble proteins changes were the parameters studied in undernourished Swiss albino mice experimentally infected with S. mansoni. Non-infected deficient animals had lower liver/body weight and spleen/body weight ratios as compared to the controls (22.60% casein group). Infected mice showed higher values regardless the type of diet. Undernourished infected subgroup showed a persistent exudative periovular reaction in the liver. Soluble hepatic proteins content and serum protein fractions appeared to be lower in the deficient infected mice. A significant difference was detected in the gammaglobulin fraction between infected and non-infected animals fed the control diet with higher values for the former. Our data suggest that the effects of malnutrition, per se, are sometimes more detrimental to the host than those due to Manson's schistosomiasis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquistossomose mansoni
/
Proteínas Sanguíneas
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Proteínas
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Desnutrição Proteico-Calórica
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Dieta
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Fígado
Limite:
Animals
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Female
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Humans
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Male
Idioma:
En
Revista:
Rev Soc Bras Med Trop
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil