Incorporation by host tissue of two biomaterials used as repair of defects produced in abdominal wall of rats.
Acta Cir Bras
; 23(1): 78-83, 2008.
Article
em En
| MEDLINE
| ID: mdl-18278397
PURPOSE: Biomaterials may be used as treatment of great abdominal wall defects to avoid tension during repair. In the present research we intended to investigate incorporation type by host tissue of membranes of microbial cellulose (MC), produced by the bacteria Zoogloea sp., and of polytetrafluoroethylene (ePTFE) in abdominal wall defects of rats. METHODS: Sixty male rats Wistar, anesthetized by ketamine (5mg/100g) and xylazine (2mg/100g), were submitted to a rectangular excision (2 x 3cm) of the abdominal wall, including fascia, muscles and peritoneum and further treated with implants of microbial cellulose (MC Group - 30 animals) or expanded polytetrafluoroethylene ( ePTFE Group- 30 animals). Each group was subdivided in 14th DPO, 28th DPO and 60th DPO Subgroups. RESULTS: Incorporation of biomaterials was observed by wrapping and infiltration by host tissue. It has been found that wrapping associated to infiltration of host connective tissue in implants of ePTFE were present in 100% of the observed samples, and this may be responsible for increase resistance to traction. Inversely, wrapping without host tissue infiltration was seen in 100% of examined specimens of MC implants. CONCLUSION: Wrapping and host tissue infiltration is seen only in ePTFE implants.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Materiais Biocompatíveis
/
Celulose
/
Implantes Experimentais
/
Parede Abdominal
Limite:
Animals
Idioma:
En
Revista:
Acta Cir Bras
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil