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A kinetic study of some factors which influence the intestinal absorption of calcium in rats.
de-Angelis, R C; Oguido, A K.
Afiliação
  • de-Angelis RC; Departamento de Fisiologia e Biofísica, Universidade de São Paulo, Brasil.
Braz J Med Biol Res ; 24(2): 215-7, 1991.
Article em En | MEDLINE | ID: mdl-1823234
Rats weighing 100 +/- 8 g were used in an in vivo kinetic study of the intestinal absorption of calcium (CaA) from three systems: 1) CaCl2, 2) whole cow's milk (M), and 3) a staple Brazilian diet (SBD). Food substrates were treated with HCl, neutralized and diluted with 0.15 mM NaCl to different concentrations. Each dilution was assayed by introducing 2 ml into the small intestine and the final amount of Ca2+ in the small intestine was determined 30 min later. The values for velocity (v = Vmax (Ca2+)/(Ca2+) + Km) and affinity (1/Km) for the food substrates were 1.35, 15.51 and 2.31 micrograms Ca2+/min and 0.29, 0.016 and 0.266 micrograms Ca2+/ml, respectively. We conclude that the higher affinities observed for CaCl2 and SBD were not correlated with velocity. Factors modifying CaA appear to be protein (stimulator) and phytate and fiber (inhibitors).
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Absorção Intestinal / Intestino Delgado Limite: Animals Idioma: En Revista: Braz J Med Biol Res Ano de publicação: 1991 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Absorção Intestinal / Intestino Delgado Limite: Animals Idioma: En Revista: Braz J Med Biol Res Ano de publicação: 1991 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil