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[Lipoprotein (a) in an urban population of Venezuela: Evidence that estrogenic deprivation increase in lipoprotein (a) levels is transitory]. / Lipoproteína (a) en una población urbana de Venezuela: evidencia de que su incremento por deprivación estrogénica es transitorio.
Bermúdez Pirela, V; Cabrera de Bravo, M; Mengual Moreno, E; Cano Ponce, C; Leal González, E; Lemus Antepaz, M; Amell de Díaz, A; Sorell Gómez, L.
Afiliação
  • Bermúdez Pirela V; Centro de Investigaciones Endocrino-Metabólicas Dr. Felix Gómez. Facultad de Medicina. Universidad del Zulia. Maracaibo, Venezuela. vbermudez@hotmail.com
An Med Interna ; 24(7): 324-7, 2007 Jul.
Article em Es | MEDLINE | ID: mdl-18020888
BACKGROUND: Lipoprotein (a) [Lp (a)] is an independent risk factor for coronary artery disease and normal serum levels of this particle is not known in our country. Thus, the aim of this study was to determine plasma Lp (a) concentration in a population sample of Maracaibo. PATIENTS AND METHOD: Fifth hundred out-patients, consulting at Centro de Investigaciones Endocrino-Metabólicas "Dr. Félix Gómez" were randomly underwent to venipunction to obtain a fasting blood simple to assess Lp (a) by a ELISA assay. RESULTS: No significantly differences were found when compared by sex or age separately, higher levels in Lp (a) was found in female 40-44 year group (median: 20,9 mg/dl). Thus, female population was divided in two sub-groups: < 40 years (median: 13 mg/dl) 40 yr and more (median: 16 mg/dl), finding higher Lp (a) levels in the second group (p < 0,02). Hormonal replace therapy was assessed by age, resulting that women subjected this approach shows lower levels of Lp (a) (p < 0,01), except in 60-64 year group. CONCLUSIONS: Lp (a) in a Maracaibo was within normal levels. Hormonal replace therapy diminishes Lp (a) concentration in menopausal women, but in menopausal women without hormonal therapy Lp (a) levels experienced a sustained decrease to normal levels in a age-depended manner.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia de Reposição de Estrogênios / Lipoproteína(a) Tipo de estudo: Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Venezuela Idioma: Es Revista: An Med Interna Assunto da revista: MEDICINA INTERNA Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Espanha
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia de Reposição de Estrogênios / Lipoproteína(a) Tipo de estudo: Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Venezuela Idioma: Es Revista: An Med Interna Assunto da revista: MEDICINA INTERNA Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Espanha