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Prevalence of COPD in five Colombian cities situated at low, medium, and high altitude (PREPOCOL study).
Caballero, Andrés; Torres-Duque, Carlos A; Jaramillo, Claudia; Bolívar, Fabio; Sanabria, Fernando; Osorio, Patricia; Orduz, Carlos; Guevara, Diana P; Maldonado, Darío.
Afiliação
  • Caballero A; Asociación Colombiana de Neumología y Cirugía de Tórax, Clínica Reina Sofía, Bogotá, Colombia. ascaballero@colsanitas.com
Chest ; 133(2): 343-9, 2008 Feb.
Article em En | MEDLINE | ID: mdl-17951621
BACKGROUND: The prevalence of COPD in Colombia is unknown. This study aimed to investigate COPD prevalence in five Colombian cities and measure the association between COPD and altitude. METHODS: A cross-sectional design and a random, multistage, cluster-sampling strategy were used to provide representative samples of adults aged >or= 40 years. Each participant was interviewed (validated Spanish version of the Ferris Respiratory Questionnaire) and performed spirometry before and after 200 microg of inhaled salbutamol, using a portable spirometer according to American Thoracic Society recommendations. COPD definitions were as follows: (1) spirometric: fixed ratio (primary definition): FEV1/FVC < 70% after bronchodilator; (2) medical: a diagnosis of chronic bronchitis, emphysema, or COPD made by a physician; (3) clinical: cough and phlegm >or= 3 months every year during >or= 2 consecutive years (chronic bronchitis). Analysis was performed using statistical software. RESULTS: A total of 5,539 orsubjects were included. The overall COPD prevalence using the primary definition (spirometric) was 8.9%, ranging from 6.2% in Barranquilla to 13.5% in Medellín. The prevalence measured by the spirometric definition was higher than medical (2.8%) and clinical (3.2%) definitions. After the logistic regression analysis, the factors related with COPD were age >or= 60 years, male gender, history of tuberculosis, smoking, wood smoke exposure >or= 10 years, and very low education level. There was a nonsignificant tendency toward larger prevalence with higher altitude. CONCLUSION: COPD is an important health burden in Colombia. Additional studies are needed to establish the real influence of altitude on COPD prevalence.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Altitude Tipo de estudo: Etiology_studies / Guideline / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Colombia Idioma: En Revista: Chest Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Altitude Tipo de estudo: Etiology_studies / Guideline / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Colombia Idioma: En Revista: Chest Ano de publicação: 2008 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos