Effect of supplementing sows' feed with alpha-tocopherol acetate and vitamin C on transfer of alpha-tocopherol to piglet tissues, colostrum, and milk: aspects of immune status of piglets.
Res Vet Sci
; 85(1): 92-100, 2008 Aug.
Article
em En
| MEDLINE
| ID: mdl-17904172
The aim of this study was to investigate the effects of dietary supplementation of sows with alpha-tocopherol acetate (ATA) and vitamin C on deposition of alpha-tocopherol (AT) in piglet lymphoid organs, such as bone marrow, thymus, and spleen at birth and at weaning, as well as on indicators of immune response in piglets. Sows were given the following treatment diets: control, vitamin C 10 g/day, ATA 500 mg/kg feed, and combined vitamins (ATA 500+Vit-C 10). Supplementation with vitamins started at the beginning of pregnancy and lasted until weaning at 21+/-3 days of age. AT was determined in colostrum, milk, piglet plasma (cord blood) and tissues at birth and on day 21. Immunoglobulins were measured in piglet plasma, milk, and colostrum. Lymphocyte proliferation in response to PHA and ConA was determined in sow and piglet blood. ATA supplementation resulted in a significant increase (P<0.001) in the AT content of colostrum, milk, piglet plasma, liver, thymus, bone marrow, and spleen at weaning. The AT content of colostrum and milk significantly (P<0.001) influenced the AT content of piglet plasma and tissues at weaning (day 21). Total Ig and IgG concentrations in piglet plasma were significantly increased in piglets given the combined vitamin treatment. No effect of AT supplementation was observed on IgG and IgA in colostrum and milk. In sows, vitamin C given alone significantly increased lymphocyte response to ConA and PHA; whereas, in piglets, there was no significant effect of treatments on lymphocyte response to PHA and ConA.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Ascórbico
/
Suínos
/
Colostro
/
Alfa-Tocoferol
/
Leite
/
Imunidade Materno-Adquirida
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Reino Unido