Poly (epsilon-caprolactone)/propolis extract: microencapsulation and antibacterial activity evaluation.
Pharmazie
; 62(4): 287-90, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-17484285
Spherical and homogenous microparticles of poly(epsilon-caprolactone) (PCL), containing propolis were prepared by the emulsification-solvent evaporation technique. Using this method of preparation, a solid formulation of propolis, free of ethanol and suitable for manipulation and storage, was obtained from an ethanolic extract of propolis. The incorporation efficiency of propolis in the microparticles was almost 30% and around 60% of the substance was released in 48 h. In vitro propolis microparticles exhibited similar halo zones in the Petri plate test against Streptococcus mutans (GS5) with a 10-fold lower concentration than the free propolis extract showing that the encapsulated propolis in microparticles is more efficient as antibiotic.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Própole
/
Bactérias
/
Caproatos
/
Lactonas
/
Anti-Infecciosos
Idioma:
En
Revista:
Pharmazie
Assunto da revista:
FARMACIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Alemanha