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Delayed developmental language milestones in children with Duchenne's muscular dystrophy.
Cyrulnik, Shana E; Fee, Robert J; De Vivo, Darryl C; Goldstein, Edward; Hinton, Veronica J.
Afiliação
  • Cyrulnik SE; Graduate Center of the City University of New York, New York, USA.
J Pediatr ; 150(5): 474-8, 2007 May.
Article em En | MEDLINE | ID: mdl-17452219
OBJECTIVES: To document the attainment of developmental milestones in children with Duchenne's muscular dystrophy (DMD) and to determine whether early delays are associated with later performance on measures of cognition. STUDY DESIGN: Retrospective parental report was utilized to document the acquisition of 10 common developmental milestones in children with DMD (n = 130) and their unaffected siblings (n = 59). Children completed tests of cognitive functioning. RESULTS: Parents rated children with DMD as delayed on achieving both language and motor milestones more frequently than their unaffected siblings. Furthermore, those children with DMD who were rated as late talkers or late walkers performed more poorly on tests of cognitive function than their on-time peers. CONCLUSIONS: In addition to the commonly reported delays in motor milestones, the current study documents delays in the acquisition of language milestones as well. These early delays are associated with significant impairments in later cognitive functioning.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distrofia Muscular de Duchenne / Transtornos do Desenvolvimento da Linguagem Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Male Idioma: En Revista: J Pediatr Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distrofia Muscular de Duchenne / Transtornos do Desenvolvimento da Linguagem Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Male Idioma: En Revista: J Pediatr Ano de publicação: 2007 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos