Symptoms reported after mass drug administration for lymphatic filariasis in Leogane, Haiti.
Am J Trop Med Hyg
; 75(5): 928-32, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17123989
Mass drug administration (MDA) for lymphatic filariasis (LF) can cause adverse reactions from microfilarial and adult worm death. Symptoms after the fifth annual MDA in Leogane, Haiti, were studied to determine whether they resulted from parasite death. Persons reporting post-MDA systemic symptoms at 5 of 148 drug distribution posts and men reporting scrotal pain at any post were interviewed. Participants were tested with immunochromatographic tests (ICTs), and men with scrotal symptoms were examined. At the five posts, 3,781 persons took anti-filarial medication. Of these, 314 (8%) returned with symptoms; the most common were headache (36%) and gastrointestinal complaints (28%). Of the 294 (94%) who consented to ICT testing, 47 (16%) were positive. Of 69 men with scrotal symptoms who consented to ICT testing, 18 (26.1%) were positive. After Leogane's fifth MDA, most symptomatic persons had undetectable levels of filarial antigen by ICT. Free symptomatic treatment may motivate some people to report symptoms and seek care.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Filariose Linfática
/
Esquema de Medicação
/
Avaliação de Programas e Projetos de Saúde
/
Resultado do Tratamento
/
Anti-Helmínticos
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Caribe
/
Haiti
Idioma:
En
Revista:
Am J Trop Med Hyg
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
Estados Unidos