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Clinical and biologic effects of granulocyte colony stimulating factor in the treatment of myelokathexis.
Weston, B; Axtell, R A; Todd, R F; Vincent, M; Balazovich, K J; Suchard, S J; Boxer, L A.
Afiliação
  • Weston B; Department of Pediatrics, University of Michigan, Ann Arbor.
J Pediatr ; 118(2): 229-34, 1991 Feb.
Article em En | MEDLINE | ID: mdl-1704431
Successful treatment of a patient with myelokathexis, a rare form of chronic neutropenia associated with recurrent infections, is described. Rapid mobilization of bone marrow neutrophils and improved myeloid morphologic features were observed after treatment with human granulocyte colony stimulating factor. Transient thrombocytopenia and bone pain were observed during treatment. Although neutrophil chemotaxis, superoxide production, and FcRIII surface expression were reduced, the patient improved clinically after restoration of a normal neutrophil count.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator Estimulador de Colônias de Granulócitos / Neutropenia Limite: Child / Female / Humans Idioma: En Revista: J Pediatr Ano de publicação: 1991 Tipo de documento: Article País de publicação: Estados Unidos
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator Estimulador de Colônias de Granulócitos / Neutropenia Limite: Child / Female / Humans Idioma: En Revista: J Pediatr Ano de publicação: 1991 Tipo de documento: Article País de publicação: Estados Unidos