Clinical and biologic effects of granulocyte colony stimulating factor in the treatment of myelokathexis.
J Pediatr
; 118(2): 229-34, 1991 Feb.
Article
em En
| MEDLINE
| ID: mdl-1704431
Successful treatment of a patient with myelokathexis, a rare form of chronic neutropenia associated with recurrent infections, is described. Rapid mobilization of bone marrow neutrophils and improved myeloid morphologic features were observed after treatment with human granulocyte colony stimulating factor. Transient thrombocytopenia and bone pain were observed during treatment. Although neutrophil chemotaxis, superoxide production, and FcRIII surface expression were reduced, the patient improved clinically after restoration of a normal neutrophil count.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator Estimulador de Colônias de Granulócitos
/
Neutropenia
Limite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
1991
Tipo de documento:
Article
País de publicação:
Estados Unidos