Improved pharmacological properties for superoxide dismutase modified with beta-cyclodextrin-carboxymethylcellulose polymer.
Biotechnol Lett
; 28(18): 1465-70, 2006 Sep.
Article
em En
| MEDLINE
| ID: mdl-16955352
Superoxide dismutase was glycosidated with cyclodextrin-branched carboxymethylcellulose. The modified enzyme contained 1.4 mol polymer per mol protein and retained 87% of the initial activity. The anti-inflammatory activity of superoxide dismutase was 2.2-times increased after conjugation and its plasma half-life time was prolonged from 4.8 min to 7.2 h.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Superóxido Dismutase
/
Carboximetilcelulose Sódica
/
Ciclodextrinas
/
Anti-Inflamatórios
Limite:
Animals
Idioma:
En
Revista:
Biotechnol Lett
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Cuba
País de publicação:
Holanda