Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura.
Pediatr Blood Cancer
; 47(5 Suppl): 737-9, 2006 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-16933257
Two hundred thirty of 696 evaluable children were identified as having chronic idiopathic thrombocytopenic purpura (ITP). Splenectomy was performed in 30 (13%), achieving remission in 22 (73%). Favorable response was associated to higher initial platelet count. Spontaneous remission was achieved by 53/200 non-splenectomized patients (26.5%), up to 10 years from diagnosis. More than half of them recovered between 6th and 12th month from diagnosis. The recovery rate was significantly higher (P=0.03) in children aged<9 years (31.2%) than in older children (14.6%). No reliable factor predictive of response in individual cases is still available.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esplenectomia
/
Púrpura Trombocitopênica Idiopática
/
Avaliação de Resultados em Cuidados de Saúde
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
Idioma:
En
Revista:
Pediatr Blood Cancer
Assunto da revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Estados Unidos