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The comparison of immobility time in experimental rat swimming models.
Calil, Caroline Morini; Marcondes, Fernanda Klein.
Afiliação
  • Calil CM; Department of Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, SP, Brazil.
Life Sci ; 79(18): 1712-9, 2006 Sep 27.
Article em En | MEDLINE | ID: mdl-16814809
Rat swimming models have been used in studies about stress and depression. However, there is no consensus about interpreting immobility (helplessness or adaptation) in the literature. In the present study, immobility time, glucose and glycogen mobilization, corticosterone and the effect of desipramine and diazepam were investigated in two different models: swimming stress and the forced swimming test. Immobility time was lower in swimming stress than in the forced swimming test. Both swimming models increased corticosterone levels in comparison with control animal levels. Moreover, swimming stress induced higher corticosterone levels than the forced swimming test did [F(2,14)=59.52; p<0.001]. Liver glycogen content values differed from one another (swimming stress
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Natação / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Natação / Modelos Biológicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Life Sci Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda