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Spectroscopic studies of stratum corneum model membrane from Bothrops jararaca treated with cationic surfactant.
Baby, André Rolim; Lacerda, Aurea Cristina Lemos; Velasco, Maria Valéria Robles; Lopes, Patrícia Santos; Kawano, Yoshio; Kaneko, Telma Mary.
Afiliação
  • Baby AR; Department of Pharmacy, School of Pharmaceutical Sciences, University of São Paulo, 580 Prof. Lineu Prestes Av., bloco 13, Conjunto das Químicas, Cidade Universitária, 05508-900 São Paulo, SP, Brazil. andrerb@usp.br
Colloids Surf B Biointerfaces ; 50(1): 61-5, 2006 Jun 01.
Article em En | MEDLINE | ID: mdl-16725316
This research employed FT-Raman and PAS-FTIR spectroscopic techniques to evaluate the interaction of cetyl trimethyl ammonium chloride (CTAC), a cationic surfactant, on the stratum corneum (SC) of shed snake skins from Bothrops jararaca, used as model membranes. Surfactant aqueous solutions (50.0 and 0.78 gl(-1)) with neutral pH were applied on the samples with intervals of 4, 8 (whole SC) and 12h (SC tape-stripped). Samples presented modifications of the topography for all conditions of the assays and the monomers of the surfactant, instead of the micelles, seemed to interact with the keratin. The SC model membranes treated with CTAC have had an augment of water content (except for whole SC treated for 8h) indicated by the expansion of the band 3600-3300 cm(-1), mainly for the tape-stripped samples after 12h treatment. Concentration appeared to be an important factor related to an increase of the tissue hydration.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tensoativos / Compostos de Cetrimônio / Epiderme / Membranas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Colloids Surf B Biointerfaces Assunto da revista: QUIMICA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tensoativos / Compostos de Cetrimônio / Epiderme / Membranas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Colloids Surf B Biointerfaces Assunto da revista: QUIMICA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda