Prevention of bacterial translocation using glutamine: a new strategy of investigation.
Nutrition
; 22(4): 419-24, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16472985
OBJECTIVE: This study investigated the role of glutamine (Gln) on bacterial translocation in an intestinal obstruction model by using Escherichia coli labeled with technetium 99m (99mTc-E. coli). METHODS: Intestinal obstruction was performed by a single ligature of the terminal ileum in rats. Animals in the control group (group 1) were sham operated (not obstructed). Experimental group 2 had intestinal obstruction. Groups 1 and 2 were not treated with Gln. Groups 3 and 4 were treated with Gln for 7 d before surgery with 250 and 500 mg x kg(-1) x d(-1), respectively. A suspension containing 100 million colony-forming units/mL of (99m)Tc-E. coli was injected into the lumen of the ileum. Twenty-four hours after surgery, blood, mesenteric lymph nodes, livers, spleens, and lungs were collected for determination of radioactivity. The Mann-Whitney U test was performed for statistical analysis. P
Assuntos
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Bacteriana
/
Escherichia coli
/
Glutamina
/
Obstrução Intestinal
Limite:
Animals
Idioma:
En
Revista:
Nutrition
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Bacteriana
/
Escherichia coli
/
Glutamina
/
Obstrução Intestinal
Limite:
Animals
Idioma:
En
Revista:
Nutrition
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos